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Fruit Fly Research May Lead to Better Understanding of Human Heart Disease

December 7, 2009
biotech

LA JOLLA, Calif., December 1, 2008¬óResearchers at the Burnham Institute for Medical Research have shown in both fruit flies and humans that genes involved in embryonic heart development are also integral to adult heart function. The study, led by Rolf Bodmer, Ph.D., was published in Proceedings of National Academy of Sciences.

Burnham Scientist Discovers Fibrosis-fighting Drug

December 7, 2009
biotech

The National Institute of Allergy and Infectious Diseases estimates that up to 45 percent of deaths in the developed world involve chronic fibrotic processes. Under a patent license from the Burnham Institute for Medical Research (Burnham) in which Burnham researcher Dr. Erkki Ruoslahti is a named inventor, Genzyme Corporation is conducting clinical trials on GC-1008, an anti-fibrotic drug.

The brains behind the Burnham Institute

December 7, 2009
biotech

ORLANDO SENTINEL, Dec. 21 — They’ve left prestigious universities and long-held research positions. Often moving across the country, a team of scientists has converged on Orlando in recent months, unpacking their test tubes and getting to work at the Burnham Institute for Medical Research.

New understanding of how to prevent destruction of a tumor suppressor

December 7, 2009
news

[NEWS]

Contact: Cindy Fox Aisen caisen@iupui.edu 317-274-7722 Indiana University School of Medicine Discovery may lead to new treatments for late-stage cancers INDIANAPOLIS – Researchers from the Indiana University School of Medicine and colleagues at the University of Texas Southwestern and Case Western University have …

Mayo Clinic researchers prove key cancer theory

December 7, 2009
news

[NEWS]

Contact: Robert Nellis newsbureau@mayo.edu 507-284-5005 Mayo Clinic Animal study demonstrates how whole chromosome changes cause cancer ROCHESTER, Minn. — Mayo Clinic researchers have proven the longstanding theory that changes in the number of whole chromosomes — called aneuploidy — can cause cancer by eli…

Delivering medicine directly into a tumor

December 7, 2009
news

[NEWS]

Contact: Josh Baxt jbaxt@burnham.org 858-795-5236 Burnham Institute Peptide delivers anti-cancer compounds to where they can do the most good (Santa Barbara, Calif.) – Researchers at Burnham Institute for Medical Research at University of California, Santa Barbara have identified a peptide (a chain of amino acids…

New approach to sickle-cell disease shows promise in mice

December 7, 2009
biotech

[NEWS]

Contact: Rob Graham rob.graham@childrens.harvard.edu 617-919-3110 Children's Hospital Boston Silencing a gene boosts production of a dormant, fetal form of hemoglobin A new genetic approach to treating sickle cell disease is showing promising results in mice, report researchers from…

Researchers demonstrate nanoscale X-ray imaging of bacterial cells

December 7, 2009
biotech

[NEWS]

Contact: Andreas Battenberg battenberg@zv.tum.de 49-892-891-2890 Technische Universitaet Muenchen Sharper vision for new insights into biological questions, including DNA repair An ultra-high-resolution imaging technique using X-ray diffraction is a step closer to fulfilling its promise as a window on nanometer-scale stru…

Study finds new relationship between gene duplication and alternative splicing in plants

December 7, 2009
biotech

[NEWS]

Contact: Sam Fahmy sfahmy@uga.edu 706-542-5361 University of Georgia Athens, Ga. – University of Georgia scientists looking to understand the genetic mechanisms of plant defense and growth have found for the first time in plants an inverse relationship between gene duplication and alternative splicing. The finding has implications for diversity not …

New platinum compound shows promise in tumor cells

December 7, 2009
biotech

[NEWS]

Contact: Jennifer Hirsch jfhirsch@mit.edu 617-253-1682 Massachusetts Institute of Technology CAMBRIDGE, Mass. – MIT chemists have developed a new platinum compound that is as powerful as the commonly used anticancer drug cisplatin but better able to destroy tumor cells. The new compound, mitaplatin, combines cisplatin with anoth…