New studies by a Roskamp Institute researcher could lead to better diagnosis and eventual treatment for U.S. military personnel and other patients with traumatic brain injuries (TBI).
“We have found that there are changes in blood proteins that occur after a head injury, and that these are dependent on the severity of the injury, the time since the injury and genetic factors influencing outcomes after head injury” said Fiona Crawford, Ph.D., associate director of the Sarasota-based Institute, a leading research center for Alzheimer’s disease and other neurological disorders. “Translating these findings from the laboratory to human patients may help clinicians determine the extent of the brain injury, how long ago the injury occurred and the patientís prognosis for a favorable or a poor outcome.”
Crawford’s research indicates that TBI can affect cellular mechanisms in the brain long after the original trauma, and that blood biomarkers reflect these ongoing processes.” TBI has multiple consequences at the cellular level and so molecular changes can persist for weeks and months after the initial brain swelling and other immediate issues have resolved,” she said.
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[...] intended to improve the quality of life for military personnel returning from Iraq and Afghanistan. Roskamp and Banyan Biomarkers are also working on [...]