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Huixin He, associate professor, nanoscale chemistry at Rutgers University, Newark, and Tamara Minko, professor at the Rutgers Ernest Mario School of Pharmacy, have developed a nanotechnology approach that potentially could eliminate the problems of side effects and drug resistance in the treatment of cancer. Under traditional chemotherapy, cancer cells, like bacteria, can develop resistance to drug therapy, leading to a relapse of the disease.

As reported in the December 21, 2009, issue of the journal Small, He, Minko and their co-researchers, including investigators from Merck & Co. and Carl Zeiss SMT, a global nanotechnology firm, have designed nanomaterials that allow for the targeted and simultaneous delivery of a chemical drug to destroy cancer cells and a genetic drug to prevent drug resistance.

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